Defending National Champion Duke and the Purdue Boilermakers have opened as co-betting favorites in college basketball odds to win the 2010-11 NCAA Men’s Basketball National Championship. Duke had been down and out as a top tier national title contender until last year when they roared back to dominance. The Blue Devils are always a name brand team that attracts plenty of public attention and following and with their return to elite status will only serve to bring additional dollars flowing their way. Duke has opened at +450 in college basketball odds to win the NCAA championship at online sportsbooks. Purdue was poised to be a Final Four contender last year before injuries did them in after they won the Big Ten regular season title.

The Butler Bulldogs and the Duke Blue Devils will both be gunning for a victory on Monday night at 9:21pm EST when they meet at Lucas Oil Stadium in 2010 NCAA championship odds for the final game of the season and the March madness tournament on CBS. College basketball betting at online sportsbooks have the Blue Devils listed as 7.5-point favorites versus the Bulldogs, while the game's total is sitting at 129. Butler toppled Michigan State 52-50 in the Final Four last time out. Heading into 2010 NCAA championship odds, the Bulldogs covered the 1.5-point spread as favorites against the Spartans, while the teams played UNDER that game's posted total of 126.

The Final Four has come down to the Top Two as the Cinderella and hometown favorite Butler Bulldogs will take on the powerful Duke Blue Devils in the NCAA Championship Game for 2010. Tipoff is set for 9:20pm EST and the game will be televised live on CBS. Duke opened as 6.5 point favorites with an over/under set at 129.5 but within hours, most online sportsbooks are reporting the Blue Devils as -7.5 favorites in college basketball odds and the total is down to 128. The game will take place at Lucas Oil Field in Indianapolis, Indiana which is where Butler is located and why they are considered the home team even if they are underdogs in college basketball picks.