College Football Predictions: Sportsbook Week 2 Lines

The tradition and passion of college football week 2 games will come to life Saturday night with a historic inter-conference match-up of historic powers when Alabama hosts Penn State at 7:05pm EST on ESPN. Both teams had easy wins over lightweights last week and the top ranked Tide is a 12-point favorite in college football predictions at online sportsbooks due to their immense reputation with the gambling public. Penn State may have the defense to hang within the number. At that same time, Tennessee will host an Oregon team that looks frightening after their blowout win last week over New Mexico. The young Vols are in the unusual position of being a 12-point home underdog in college football lines. Also at 7:05pm EST will be Wyoming vs Texas and Louisiana Tech vs Texas A&M.

Wyoming could be a dangerous 29-point college football betting underdog while the Aggies offense looks explosive as they are 19.5-point favorites against rebuilding Tech. Ole Miss is coming off a catastrophic loss to 1-AA Jacksonville State and will travel to Tulane. The Rebels desperately need a win to take away the sting and are a 20.5-point favorite in college football predictions for week 2 for the ESPN2 game at 9:05pm EST. ESPN will feature the Pac-10 Conference opener of Stanford vs UCLA at 10:35pm EST. Stanford is a small 6-point favorite in week 2 lines against a UCLA team that suffered a painful defeat at Kansas State last week. Both teams are considered contenders in the wide open Pac 10 race.

Fox Sports Net will offer an inter-sectional/inter-conference match-up of USC hosting Virginia in the home debut of Lane Kiffin. The Trojans won last week at Hawaii but the defense was very leaky and that has alarmed many sports betting handicappers heading into college football week 2 lines. Matt Barkley was sharp at quarterback for the Men of Troy who have great front line talent on offense but lack depth which is why USC has opened at online sportsbooks as 19.5-point favorites in week 2 college football predictions.